12 November 2020 to 12 November 2020
Online Webinar
Online Webinar
United States
Free webinar
Speaker: Dr. Richard Hark
Conservation Scientist, Yale Center for British Art and the Beinecke Rare Books and Manuscripts Library
Time: 12:00 - 1:00 pm EST (Log-in: 11:45 am)



![Targeted proton transfer charge reduction (tPTCR) nano-DESI mass spectrometry imaging of liver tissue from orally dosed rat (Animal 3). a) optical image of a blood vessel within liver tissue. b) Composite ion image of charge-reduced haeme-bound α-globin (7+ and 6+ charge states; m/z 2259.9 and m/z 2636.3 respectively, red) and the charged-reduced [FABP+bezafibrate] complex (7+ and 6+ charge states; m/z 2097.5 and m/z 2446.9 respectively, blue). c) Ion image composed from charge-reduced haeme-bound α-globin (7+ and 6+ charge states) showing abundance in blood vessels. d) Ion image composed from charge-reduced [FABP+bezafibrate] complex (7+ and 6+ charge states) showing abundance in bulk tissue and absence in the blood vessel. Reproduced from https://doi.org/10.1002/ange.202202075 under a CC BY licence. Light and mass spectromert imaging of tissue samples](/sites/default/files/styles/see_also/public/news/MSI%20drug-protein%20complex-w.jpg?itok=K57jqSou)




