23 November 2020 to 24 November 2020
Montpellier
Montpellier
France
[email protected]This workshop will present the fundamental and applied aspects of Mass Spectrometry-based structural techniques, as well as data analysis procedures. State-of-the-art lectures will be given by experts in the field, destined to both non-MS and MS specialists.
Phase II is a technical workshop giving hands-on experiments to apply main fundamental aspects developed during Phase 1 of the workshop.
Three different training are proposed together with dedicated bioinformatics tools for data analysis:
- Native and Ion Mobility MS to analyse multiproteic and ligand binding complexes (IGF, Montpellier, November 23-24 2020).
- Top-Down MS to identify proteoforms from an immunoprecipitation (IPBS, Toulouse, November 16-17 2020).
- HDX-MS to study the deuteration of standard proteins (IPHS, Strasbourg ,November 30-December 1, 2020).
Other events in



![Targeted proton transfer charge reduction (tPTCR) nano-DESI mass spectrometry imaging of liver tissue from orally dosed rat (Animal 3). a) optical image of a blood vessel within liver tissue. b) Composite ion image of charge-reduced haeme-bound α-globin (7+ and 6+ charge states; m/z 2259.9 and m/z 2636.3 respectively, red) and the charged-reduced [FABP+bezafibrate] complex (7+ and 6+ charge states; m/z 2097.5 and m/z 2446.9 respectively, blue). c) Ion image composed from charge-reduced haeme-bound α-globin (7+ and 6+ charge states) showing abundance in blood vessels. d) Ion image composed from charge-reduced [FABP+bezafibrate] complex (7+ and 6+ charge states) showing abundance in bulk tissue and absence in the blood vessel. Reproduced from https://doi.org/10.1002/ange.202202075 under a CC BY licence. Light and mass spectromert imaging of tissue samples](/sites/default/files/styles/see_also/public/news/MSI%20drug-protein%20complex-w.jpg?itok=K57jqSou)





